In the same year, depression was the main reason for work incapacity and for early retirement among women. For instance, in Berlin, Germany, the prevalence of lifetime depression in 2008 was almost 20% for women between 18 and 29 years old, 25% for women between 40 and 59 years old and, among men, 12% and 15% for the same age groups, respectively. The prevalence can be higher in some age groups. The overall prevalence of depressive disorders in five European countries was 8.56%, with a higher prevalence in urban Ireland (12.3%) and urban United Kingdom (UK, 17.1%). The estimated global burden of disease from major depression, measured as "disability adjusted life years" (DALY), is rising globally, making depression the leading cause of DALYs in middle and high income countries. From 120 million people that suffer from depression around the world, less than 25% receive adequate treatment.
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